HDV is a defective virus, which can be replicated by relying on HBsAg. It is characterized by simultaneous or overlapping infection of HDV and HBV. The main route of transmission is life contact, and it can also be transmitted through blood products, blood transfusion, injection and the like. Its laboratory tests are mainly to detect antigens and antibodies.

Basic Information

Specialist classification: Infectious disease examination and classification: liver function examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:

Normal value:
no

Above normal:

negative:
normal.

Positive:
Hepatitis D has been infected and is contagious.

Tips: It should be light, eat more fruits and vegetables, mix food reasonably, pay attention to adequate nutrition. Normal value

negative.

Clinical significance

The anti-HDV assay in serum contributes to the diagnosis of HDV infection, especially high titers can be diagnosed as chronic HDV infection. Anti-HDV-IgG positive in HBsAg-positive patients is a reliable indicator for the diagnosis of hepatitis D, even after the termination of HDV infection for many years. Anti-HDV-IgM positivity indicates acute or recent HDV infection, which contributes to the early diagnosis of the disease and distinguishes between HBV and HDV infections or overlapping infections. At the same time, transient anti-HDV-IgM often appeared, and then anti-HDV-IgG appeared or not; anti-HDV-IgM increased continuously with overlapping infection, accompanied by anti-HBV-IgG positive, symptoms worsened, and the prognosis was poor.

Precautions

HDV itself is not infected and can only be infected with HBsAg-positive people. HDVAg is highly antigenic and can stimulate the body to produce IgG and IgM antibodies. These antibodies are non-neutralizing antibodies and have no protective effect on the body.

Inspection process

According to the kit instructions, or refer to the following method: 50 μl of serum to be tested per well, set positive and negative controls, wash at 37 ° C for 1 h. HPR-goat anti-human IgG was added, 50 μl per well, and washed at 37 ° C for 1 h. The TMB-H2O2 substrate was added for color development at room temperature for 15 min.

Not suitable for the crowd

Those who do not have an indication for examination should not do this check.

Adverse reactions and risks

1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding.

2. Risk of infection: If you use an unclean needle, you may be at risk of infection.