Group A beta-hemolytic streptococcus can produce hyaluronidase, which is antigenic and can stimulate the body to produce antibodies, ie antihyaluronidase (AH). Determination of AH in serum helps to determine streptococcus Whether the infection exists. A certain amount of blood is taken for testing, and AH in the serum is measured from the drawn blood for correct judgment of normal or abnormal.

Basic Information

Specialist classification: Infectious disease examination and classification: blood examination

Applicable gender: whether men and women apply fasting: fasting

Tips: People who take a lot of antibiotics or hormones are not suitable for this test. Normal value

Normal value: <1:128.

Clinical significance

(1) Patients with rheumatic fever have a positive serum AH. It is of great value for the diagnosis of rheumatic fever when the antibody titer is gradually increased or the titer is ≥1:256. In patients with rheumatic fever, serum AH elevation is often earlier than ASO, and the duration of continuous increase is significantly longer than ASO. Therefore, the diagnostic value of rheumatic fever is higher than that of ASO.

(2) Other group A hemolytic streptococcal infection-related diseases such as acute glomerulonephritis, tonsillitis, etc., serum AH can also be elevated.

(3) AH elevation is evidence of the presence of streptococcal infection, not a direct demonstration of rheumatic fever.

High results may be diseases: rheumatic fever, pediatric rheumatic fever, precautions for nephritis after acute infection in the elderly

Inappropriate people: People who take large amounts of antibiotics or hormones.

Pre-examination contraindications: Hypercholesterolemia, multiple myeloma and macroglobulinemia may cause false positives; false positives may occur when patients are treated with a large number of antibiotics or hormones in the early stages of onset.

Requirements for inspection: Pay attention to the doctor's examination.

Inspection process

A certain amount of blood needs to be taken for testing, and AH in the serum is measured from the drawn blood for correct judgment of normal or abnormal.

Not suitable for the crowd

Those who do not have an indication for examination should not do this check.

Adverse reactions and risks

Generally no complications and harm.