The pH of the normal gastric juice is 0.9 to 1.8. If the pH is 0.9, the acidity is too high, the pH is 3.5 to 7.0, and the pH is 7.0, which is acid-free. 3 days before the collection of gastric juice, various drugs that affect gastric acid secretion, such as omeprazole, cimetidine, etc., and drugs affecting gastric acid pH, such as sodium bicarbonate, were discontinued.

Basic Information

Specialist classification: Digestive examination classification: body fluid examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:
Increased gastric acidity, pH less than 0.9, seen in duodenal ulcer, Zhuo-Ai syndrome, pyloric obstruction, chronic cholecystitis, etc., duodenal fluid reflux will also increase the pH.

Normal value:
Gastric juice pH: 0.9-1.8

Above normal:
Reduced gastric acidity, pH 3.5 ~ 7.0, common in atrophic gastritis, gastric cancer, secondary iron deficiency anemia, gastric dilatation, hyperthyroidism. The decrease in gastric acidity is seen in duodenal reflux, gastric ulcer, gastric cancer, atrophic gastritis, chronic gastritis, and pernicious anemia.

negative:

Positive:

Tips: Stop the various drugs that affect gastric acid secretion 3 days before the collection of gastric juice. Normal value

pH 0.9 to 1.8.

Clinical significance

1, pH 3.5 ~ 7.0, gastric acidity is reduced, common in atrophic gastritis, gastric cancer, secondary iron deficiency anemia, gastric dilatation, hyperthyroidism. Gastric acidity reduction is also seen in duodenal reflux, gastric ulcer, gastric cancer, atrophic gastritis, chronic gastritis, and pernicious anemia.

2, the pH is less than 0.9, the increase in gastric acidity is seen in duodenal ulcer, Zhuo-Ai syndrome, pyloric obstruction, chronic cholecystitis, etc., duodenal fluid reflux will also increase the pH.

High results may be diseases: strong alkali poisoning, duodenogastric reflux and bile reflux gastritis, gastric cancer, full attention

3 days before the collection of gastric juice, various drugs that affect gastric acid secretion, such as omeprazole, cimetidine, etc., and drugs affecting gastric acid pH, such as sodium bicarbonate, were discontinued.

Inspection process

1. For each specimen to be tested, first measure the pH value with a pH test paper, and determine the acidity. If the pH is >3, the acid ion concentration is accurately determined by a pH meter.

2. Take 5ml of clarified gastric juice and add 2 drops of 0.2g/L phenol red indicator (if it is yellow, it means there is stomach acid). Titrate with 0.1 mol/L NaOH solution until the initial red color (end point pH 7.0), multiply the number of NaOH mL consumed by 20, which is the content of mmol/L per liter of gastric acid concentration (divide by 1000 to be per ml) Gastric acid concentration).

Not suitable for the crowd

Patients with gastric perforation.

Adverse reactions and risks

Mucosal injury: Avoid excessive exertion when removing gastric juice from the gastric tube to avoid damage to the nasal cavity and esophageal mucosa.