The fibrin lysate is separated from the different fibrin polypeptides in the pretreated samples by high performance liquid chromatography, and compared with the standard, the content of FPBβ15-42 is detected. The protein or polypeptide can be redistributed and separated in chromatography according to the relative molecular mass, and the content of fibrin peptide Bβ15-42 is detected by fluorescence chromatography.

Basic Information

Specialist classification: cardiovascular examination classification: biochemical examination

Applicable gender: whether men and women apply fasting: fasting

Tips: Immediately after blood collection, inject into the test tube containing anticoagulant and mix it quickly in ice water. If it needs to be preserved, it is better to use -20 °C after adsorption treatment with bentonite. Normal value

Fluorescence chromatography 1.56 ± 1.20 pmol / L.

Clinical significance

1, increased in thrombosis, malignant tumors, uremia, disseminated intravascular coagulation (DIC), acute and chronic leukemia.

2, reduce the incidence of bleeding disorders.

High results may be diseases: disseminated intravascular coagulation, thromboangiitis obliterans, malignant tumors, uremia considerations

1, blood collection should be smooth, should not be > 45s, and the first 2ml discarded, the syringe should be silicified or with a plastic syringe.

2. Immediately after blood collection, inject into the test tube containing anticoagulant and mix it quickly in ice water. If it needs to be preserved, it should be -20 °C after adsorption treatment with bentonite.

Inspection process

Fluorescence chromatography: Proteins or peptides can be redistributed and separated in chromatography according to the relative molecular mass. The content of fibrin peptide Bβ15~42 is detected by fluorescence chromatography.

Not suitable for the crowd

no.

Adverse reactions and risks

no.