The α-hydroxybutyrate dehydrogenase is not a separate specific enzyme, but a general term for LD-1 and LD-2 containing the H subunit. Determination of α-hydroxybutyrate dehydrogenase, which actually reflects the activity of lactate dehydrogenase isoenzymes LDH1 and LDH2, has a certain significance for the diagnosis of myocardial disease and liver disease.

Basic Information

Specialist classification: cardiovascular examination classification: biochemical examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:
Found in the application of immunosuppressive agents, anticancer agents (LDA also reduced), genetic variation of LDH-H subtype deficiency (LDH / α-HBDH ratio decreased).

Normal value:
α-HBDH: 90-220U/L

Above normal:
Elevation can be seen in 1, acute myocardial infarction, pernicious anemia, hemolytic anemia, teratoma (increased proportion of LDH / α-HBDH). 2, leukemia, lymphoma, infectious mononucleosis (LDH / α-HBDH ratio does not increase).

negative:

Positive:

Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. Fasting for 12 hours before taking blood, taking fresh blood for examination. Normal value

Enzyme rate method (37 ° C) 90 ~ 220U / L.

Clinical significance

Abnormal result

First, the increase can be seen in:

1, acute myocardial infarction, pernicious anemia, hemolytic anemia, teratoma (increased proportion of LDH / α-HBDH).

2, leukemia, lymphoma, infectious mononucleosis (LDH / α-HBDH ratio does not increase).

Second, the reduction can be seen in:

The use of immunosuppressive agents, anticancer agents (LDA is also reduced), genetic variation of LDH-H subtype deficiency (LDH / α-HBDH ratio decreased).

High results may be diseases: pediatric myocarditis, teratoma, acute myocardial infarction, infectious mononucleosis, leukemia, hemolytic anemia precautions

Before inspection:

1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results.

2. Fasting for 12 hours before taking blood, taking fresh blood for inspection.

When checking:

When you draw blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection.

After inspection:

1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma.

2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended.

3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.

4. If there is localized congestion, use a warm towel after 24 hours to promote absorption.

Inspection process

The blood of the subject is extracted and detected by enzymatic method.

Not suitable for the crowd

Unsuitable people: The people who need to be tested are those with abdominal distension, abdominal pain, myocardial infarction, anemia, leukemia, and cirrhosis.

Adverse reactions and risks

Risk of infection: If you use an unclean needle, you may be at risk of infection.