Serum amylase isoenzyme (AMY-I)

In addition to the pancreas, serum amylase is also derived from the salivary gland and many other tissues. Therefore, when the amylase activity is increased, the determination of isoenzymes contributes to the differential diagnosis of the disease. The agarose electrophoresis method can divide the amylase isoenzyme into two types, namely, S type (saliva type) and P type (pancreatic type). When P-isoenzymes are elevated or decreased, there may be pancreatic disorders; changes in S-isozymes may be due to salivary glands or other tissues. When serum amylase activity is elevated and undiagnosed, isozymes should be further determined to aid differential diagnosis. There are many ways to determine isozymes, and agarose and vinegar membrane electrophoresis are common methods.

Basic Information

Specialist classification: Digestive examination classification: biochemical examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:

Normal value:
AMY-P (pancreatic): 8-45U/L
AMY-S (saliva type): 8-70U/L

Above normal:
1, AMY-P elevation can be seen in acute pancreatitis. 2, AMY-S elevated in mumps, renal failure, cancer.



Tips: The blood test results have little to do with eating, and there is no need to fasting blood. Normal value

Enzyme inhibition method (37 ° C)

AMY-P (pancreatic) 8 ~ 45U / L (mainly in the urine).

AMY-S (saliva type) 8 ~ 70U / L (mainly in blood).

(Note the specific reference value depends on each laboratory.)

Clinical significance

1, AMY-P elevation can be seen in acute pancreatitis.

2, AMY-S elevated in mumps, renal failure, cancer.

High results may be diseases: acute pancreatitis, mumps, renal failure precautions

1. The use of oral contraceptives, codeine, morphine, anesthetics, and sulfonamides that have been contaminated with saliva will result in low specimen determination results.

2, blood test results and eating relationship is not big, blood does not need to be fasting.

Inspection process

Immediately after blood collection, the test was carried out, and the detection method was determined by the enzyme inhibition method.

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Adverse reactions and risks