PH is the basis for collagen to maintain a three-helix stable structure and is a key step in collagen synthesis. PH is a glycoprotein. The intrahepatic PH activity gradually increases with the progression of liver fibrosis. The activity of the enzyme mainly reflects the activity of liver fibrosis. The serum immunoreactive pH content was determined by monoclonal antibody, which was significantly increased in chronic active hepatitis with detrital necrosis, inflammation and active cirrhosis. Serum PH level was correlated with liver fibrosis and serum PIIIP level.

Basic Information

Specialist classification: Digestive examination classification: biochemical examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:
Rare.

Normal value:
Serum proline hydroxylase: 20.8-58.2μg/L

Above normal:
Elevated in liver cirrhosis, chronic hepatitis active period, alcoholic hepatitis. Non-hepatic fibrosis, such as obstructive jaundice, acute hepatitis, metastatic liver cancer, and an infectious disease may also increase.

negative:

Positive:

Tips: Non-hepatic fibrosis, such as obstructive jaundice, acute hepatitis, metastatic liver cancer and an infectious disease can also increase. Normal value

Radioimmunoassay (RIA) 20.8 to 58.2 μg/L.

Clinical significance

Elevated in liver cirrhosis, chronic hepatitis active period, alcoholic hepatitis. Non-hepatic fibrosis, such as obstructive jaundice, acute hepatitis, metastatic liver cancer, and an infectious disease may also increase.

High results may be diseases: alcoholic hepatitis, cirrhosis, metastatic liver cancer

Non-hepatic fibrosis, such as obstructive jaundice, acute hepatitis, metastatic liver cancer, and an infectious disease may also increase.

Inspection process

Immediately after venous blood collection, the test method was determined by radioimmunoassay.

Not suitable for the crowd

no.

Adverse reactions and risks

no.