Serum chromium (Cr)

The total amount of chromium in adults is about 6 mg. Chromium is absorbed by the intestinal tract in the form of a trivalent state small molecular weight organic complex. Determination of chromium in serum helps to diagnose diseases such as chromium poisoning, and is often combined with urinary chromium content in clinical practice. Chromium is mainly discharged from the urine. Chromium can increase the breakdown and excretion of cholesterol, lower blood cholesterol, and prevent the formation of arteriosclerosis. Chromium is also an effective component of the glucose tolerance factor (functioning to assist insulin in the use of glucose). Therefore, the chromium content in the body is negatively correlated with the incidence of cardiovascular disease. The protective effect of chromium on cardiovascular is related to its involvement in sugar and lipid metabolism.

Basic Information

Specialist classification: growth and development check classification: biochemical examination

Applicable gender: whether men and women apply fasting: fasting

Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. Fasting should be fast after 8 pm on the day before the medical examination, so as not to affect the detection of indicators such as blood glucose in the second sky. Normal value

Atomic absorption spectrophotometry (AAS): whole blood <13.4 μmol/L; serum <2.7 μmol/L.

Clinical significance

1, reduced in atherosclerosis, coronary heart disease, diabetes and primary hemochromatosis.

2, increased in acute chrome poisoning. Oral dichromate poisoning is more common, can cause corrosive gastroenteritis after a few minutes of service, severe cases may have purpura, and even acute renal failure, serum chromium, urinary chromium increased significantly.

Low results may be diseases: coronary heart disease, atherosclerosis considerations

First, the precautions before blood draw

1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results.

2. After 8 pm on the day before the physical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky.

3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection.

Second, should pay attention after blood draw

1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma.

2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended.

3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.

4. If there is localized congestion, use a warm towel after 24 hours to promote absorption.

Inspection process

1. Take an appropriate amount of blood and immediately send it for inspection.

2. The blood sample is diluted with the matrix modifier solution, directly injected into the pyrolytic coated graphite tube, sequentially dried, ashed and atomized at different temperatures set, and then the absorbance is read at a wavelength of 283.3 nm. The Cr concentration corresponding to the absorbance value was found under the standard curve.

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Adverse reactions and risks