The haptoglobin, also known as haptoglobin, is an α2 globulin synthesized by the liver, which accounts for about 1% of total plasma protein and binds to hemoglobin in plasma to form a stable complex. When hemolysis occurs, the amount of free hemoglobin in the plasma increases, the amount of globin bound to it increases, and the plasma haptoglobin decreases, which is a very sensitive indicator of intravascular hemolysis.

Basic Information

Specialist classification: growth and development examination classification: blood examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:
The reduction or disappearance of haptoglobin is mainly seen in various intravascular hemolytic anemia. In addition, the combination of globin in liver disease and infectious mononucleosis can also be reduced.

Normal value:
Serum binding globulin: 0.5-1.5g/L

Above normal:
Acute and chronic infections, tuberculosis, autoimmune diseases, tumors and hormonal drugs can be combined with globin.

negative:

Positive:

Tips: Pay attention to whether the specimen has hemolysis. If there is hemolysis, the specimen should be kept. Normal value

0.5 to 1.5 g/L (50 to 150 mg/100 ml).

Clinical significance

1. The reduction or disappearance of haptoglobin is mainly seen in various intravascular hemolytic anemia. In addition, the combination of globin in liver disease and infectious mononucleosis can also be reduced.

2, combined with globin increased acute and chronic infection, tuberculosis, autoimmune system diseases, tumors and taking hormone drugs, combined with globin can be increased.

Low results may be diseases: tuberculosis, infectious mononucleosis, high results may be diseases: microvascular disease hemolytic anemia considerations

Note that the specimen has no hemolysis, and if there is hemolysis, the specimen should be kept.

Inspection process

Immediately after venous blood collection, the test method was determined by electrophoresis.

Not suitable for the crowd

no.

Adverse reactions and risks

no.