There are many enzymes in the human body involved in the functions of substance metabolism, energy conversion, and nerve conduction and immunomodulation. In 1972, the International Committee of Enzymes divided the enzyme assay into six categories, namely oxidoreductase, transferase, hydrolase, lyase, ligase, isomerase and the like. The PHI assay is usually performed by the Brinell method. RA (rheumatoid arthritis) is an antigen-driven and T cell-mediated systemic autoimmune disease. There are GPI antigens in the serum and in the joint effusion of RA patients and about 64% of healthy people and RA uncontrolled patients. GPI is mainly secreted by the in vivo T cell system and the B lymphocyte system. A large number of GPI antigens enter the serum and joint cavity, which increases the concentration of GPI in serum and joint cavity, and is a unique autoimmune function of RA. Patients with RA have a high concentration of GPI, often accompanied by severe joint function limitation, suggesting that the prognosis is poor or the drug does not play a role in the treatment. When RA patients are treated with medication, the concentration of GPI in serum and joint effusion is reduced, and joint swelling and pain are alleviated. The concentration of GPI was positively correlated with joint swelling and pain in GA patients; it was not associated with other autoimmune diseases such as inflammation, tumors, and various types of hepatitis. The experimental indicators have important value for the early differential diagnosis of RA disease, understanding the occurrence, development, treatment and prognosis of the disease. It is statistically significant in the RA active and inactive groups.

Basic Information

Specialist classification: inspection classification: biochemical examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:
normal.

Normal value:
Serum phosphohexose isomerase: 8-10U

Above normal:
Acute hepatitis is extremely elevated, myocardial infarction, acute nephritis, cerebral hemorrhage is significantly elevated, malignant tumors, acute and chronic myelogenous leukemia, chronic hepatitis, cirrhosis, obstructive jaundice normal or slightly higher.

negative:

Positive:

Tips: PHI activity is high in mature red blood cells of newborns. Normal value

Bodansky method (Brinell method) 8 ~ 10U.

Clinical significance

Elevation: acute hepatitis is extremely elevated, myocardial infarction, acute nephritis, cerebral hemorrhage is significantly elevated, malignant tumors, acute and chronic myelogenous leukemia, chronic hepatitis, cirrhosis, obstructive jaundice normal or slightly higher .

High results may be diseases: myocardial infarction, acute nephritis, chronic myeloid leukemia, malignant tumors

PHI activity is higher in mature red blood cells of newborns.

Inspection process

The same Brinell method.

Not suitable for the crowd

no.

Adverse reactions and risks

no.