Ornithine carbamoyltransferase is an aminotransferase mainly located in the mitochondria of liver cells and is a specific enzyme of the liver. It is most abundant in the liver, and other tissues such as the small intestine are basically absent. Its role is to catalyze the reversible transformation of ornithine to citrulline, which has important physiological functions in the body, and is a key step in the production of urea by ammonia in hepatocytes. Determination of ornithine carbamoyltransferase is a sensitive indicator of hepatobiliary disease.

Basic Information

Specialist classification: Digestive examination classification: biochemical examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:
Reduced in premature infants, ornithine carbamoyltransferase deficiency and the like.

Normal value:
Serum ornithine carbamoyltransferase: 8-20u/L

Above normal:
Significantly elevated in acute viral hepatitis, liver cancer, hepatocyte necrosis, acute liver damage caused by drugs or acute pancreatitis, severe shock and other patients. Mild or moderate elevation is seen in cirrhosis, gallstones, chronic alcoholism, chronic hepatitis, liver abscess, primary or secondary liver cancer, liver trauma, various operations, post-radiation therapy, acute enteritis.

negative:

Positive:

Tips: Before the examination, the diet is light and alcohol is prohibited. Check for an empty stomach in the morning. Normal value

8 ~ 20u / L.

Clinical significance

1, reduced in premature infants, ornithine carbamoyltransferase deficiency and so on.

2, elevated: significantly elevated in acute viral hepatitis, liver cancer, hepatocyte necrosis, acute liver damage caused by drugs or acute pancreatitis, severe shock and other patients. Mild or moderate elevation is seen in cirrhosis, gallstones, chronic alcoholism, chronic hepatitis, liver abscess, primary or secondary liver cancer, liver trauma, various operations, post-radiation therapy, acute enteritis.

High results may be diseases: viral hepatitis, gallstones, liver cancer precautions

High protein dieters can slightly increase the results.

Inspection process

The appropriate amount of blood was taken intravenously and measured by the enzyme speed method.

Not suitable for the crowd

no.

Adverse reactions and risks

no.