Serum iron (Fe)

Iron is an essential element of the human body. The total amount of iron in normal adults is 71.63~89.54mmol/L, of which about 2/3 has physiological activity and 1/3 is storage iron. The physiologically active iron is present in the form of heme, which is mainly in the form of heme, and therefore, iron deficiency causes anemia. Determination of serum iron can diagnose iron deficiency anemia.

Basic Information

Specialist classification: growth and development check classification: biochemical examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:
Can be seen in iron deficiency anemia.

Normal value:
Adult male: 11.0-30.0μmol/L
Adult woman: 9.0-27.0μmol/L
Children: 9.0-32.2μmol/L
Old age: 7.2-14.4μmol/L

Above normal:
Common red blood cell damage increases.



Tips: Serum iron is highest in the morning, and gradually decreases in the afternoon. Blood samples should be taken in the morning on an empty stomach. Normal value

Adult males are 11.0 to 30.0/μmol/L (61 to 167 μg/dl).

The adult woman is 9.0 to 27.0 μmol/L (50 to 150 μg/dl).

Children 9.0 ~ 32.2 μmol / L (50 ~ 180μg / dl).

Old age 7.2 ~ 14.4 μmol / L (40 ~ 80μg / dl).

Clinical significance

1. Pathological increase

1. Increased destruction of red blood cells, such as hemolytic anemia;

2, red blood cell regeneration or maturation disorders, such as aplastic anemia, megaloblastic anemia;

3, the utilization of iron is reduced, such as lead poisoning or vitamin B6 deficiency caused by decreased hematopoietic function;

4. Increased release of stored iron, such as acute liver cell damage, necrotizing hepatitis, etc.;

5, the absorption rate of iron increased, such as hemochromatosis, hemosiderosis;

6, repeated blood transfusion treatment or intramuscular injection of iron caused by acute poisoning.

2. Pathological reduction

1. Insufficient intake of the body, such as malnutrition, gastrointestinal diseases, peptic ulcer, chronic diarrhea, etc.;

2, the body loses iron, such as blood loss, including massive and hidden blood loss, especially nephritis, kidney tuberculosis, vaginal bleeding, ulcer disease, etc., genitourinary tract and gastrointestinal bleeding;

3. The need for iron in the body is increased and not replenished in time, such as pregnancy, baby growth period, etc.;

4, the reduction of iron release in the body, such as acute and chronic infections, uremia, etc. can cause iron release reduction;

5, certain drug treatments, such as adrenocorticotropic hormone or adrenocortical hormone, large doses of aspirin, cholestyramine and so on.

3. Physiological reduction

Women in the menstrual period, pregnancy, infants in the growing season, due to increased iron requirements in the body, can reduce serum iron, is a physiological phenomenon.

Low results may be diseases: nutritional anemia, high results of hemolytic anemia may be diseases: aplastic anemia, idiopathic hemosiderin precautions

1. Serum iron is highest in the morning in 1 day and gradually decreases in the afternoon. Blood samples should be taken on an empty stomach in the morning.

2, before the examination, use iron to treat or fast foods with high iron content, such as animal liver; fasting energy and iron complex substances, such as tea.

Inspection process

Mix and boil in boiling water for 5 min. After cooling, centrifuge to precipitate, take the supernatant, colorimetrically with 530 nm or green filter, adjust the absorbance to 0 point with a blank tube, and read the absorbance of each tube.

Not suitable for the crowd

Generally there are no people who are not suitable.

Adverse reactions and risks

Subcutaneous hemorrhage: subcutaneous hemorrhage due to less than 5 minutes of compression time or blood draw technique.