Transferrin (Tf) is an important β1-globulin with a molecular weight of 77,000 and a compound containing 6% sugar. It has the function of transporting iron. The Tf of each molecule carries 2 iron atoms. Tf can bind 1.25 μg of iron. TF can be used for the diagnosis and treatment of anemia, the level of TF is increased in iron deficiency hypoehtemia, and the FT is normal or low. Transferrin is mainly synthesized in the liver, and its reduction can be used as an indicator to judge the prognosis of liver disease.Basic Information
Specialist classification: Digestive examination classification: blood examination
Applicable gender: whether men and women apply fasting: fastingTips: Women in the late pregnancy, oral contraceptives, transferrin can be elevated. Normal value
2.5-4.3g/L. (immunotactic turbidimetry)Clinical significance
1, transferrin is mainly synthesized in the liver, but in turn can promote the regeneration of liver cells, so some people use transferrin as an indicator of the prognosis of liver disease. Some patients with acute hepatitis have elevated TF, and chronic hepatitis and malnutrition decline.
2, TF can be used for the diagnosis and treatment of anemia, TF levels increase in iron deficiency hypoandice anemia, normal or low aplastic anemia FT.
3. Plasma TF can be increased during pregnancy and oral contraceptives or estrogen injection.Low results may be diseases: pediatric protein-energy malnutrition, hemolytic anemia results may be high disease: iron deficiency anemia considerations
1. Women in the late pregnancy, oral contraceptives, transferrin can be elevated.
2. Reference value of adult urine transferrin determination: 0.68mg/24h. Increased levels of urinary transferrin are mainly seen in diabetic nephropathy.Inspection process
The serum to be tested was diluted 100 times with physiological saline and operated according to Table 1.
Mix and set at room temperature for 30 min, both excitation and scattered light are 450 nm, and the fluorescence is corrected to zero by diluting the blank tube. The fluorescence readings of each tube were read separately.Not suitable for the crowd
Special diseases: Patients with hematopoietic dysfunction, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood.Adverse reactions and risks
1, local subcutaneous hemorrhage: after the blood collection should be pressed for a sufficient time, especially those with bleeding tendency, so as not to cause subcutaneous oozing and bruising due to no blood coagulation.
2, infection: attention to aseptic operation during venous blood collection, so as not to cause local infection.