HBcAb-IgG appears late and is not a protective antibody. The recovery period of acute infection and chronic persistent infection are mainly anti-HBc-IgG, which can last for several years. The detection of HBcAb-IgG has epidemiological significance. It has been proposed to simultaneously detect anti-HBc-IgM and anti-HBc-IgG, and compare the titers of both, such as IgM predominating for the recent infection, while IgG predominating for the previous infection.

Basic Information

Specialist classification: Infectious disease examination and classification: blood examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:

Normal value:
no

Above normal:

negative:
normal.

Positive:
Prompt immunity, no infection, only history of hepatitis B infection.

Tips: According to the nutritional status of the whole body, milk, eggs, fruits, soy milk, etc. are given in the meal. Normal value

negative.

Clinical significance

1. Anti-HBc IgG alone shows immunity, no infection, only history of hepatitis B infection.

2. Both anti-HBcIgM and anti-HBcIgG positive hepatitis B tend to be chronic.

Positive results may be diseases: hepatitis B, hepatitis B virus precautions

It has been proposed to simultaneously detect anti-HBc-IgM and anti-HBc-IgG, and compare the titers of both, such as IgM predominating for the recent infection, while IgG predominating for the previous infection.

Inspection process

1, according to the material: blood.

2, Hepatitis B core antibody immunoglobulin G determination principle: the same as anti-HAVIgM, using the sandwich method ELISA.

3, reagents: domestic commercial kits, containing anti-μ chain coated reaction plate (strip), hepatitis B virus core antigen HBcAg application solution, anti-HBcHRP application solution and anti-HBc-IgG negative, positive control serum , sample diluent, washing solution, substrate solution and stop solution and other reagents.

4. Operation method: Follow the instruction manual of the kit. The general kits are divided into two categories, namely a three-step method and a two-step method, and the specific operation is the same as the anti-HAV-IgM detection method.

Not suitable for the crowd

Generally no taboos.

Adverse reactions and risks

Generally no complications and harm.