Carbon dioxide binding

Carbon dioxide binding is the amount of carbon dioxide dissolved in plasma or serum at a specific temperature and pressure, that is, the patient's plasma is equilibrated with normal human alveolar gas (pCO2 is 5.32 kPa) under air-insulated conditions. The measured plasma CO2 content, minus the value of the known CO2 fraction dissolved in plasma, reflects the amount of alkali storage in the body, mainly used to understand the content of sodium bicarbonate in the blood, to determine whether there is acid-base balance Disorder and its extent, determine the function of the kidney to regulate acid-base balance.

Basic Information

Specialist classification: Respiratory examination classification: pulmonary function test

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:
Found in metabolic acidosis.

Normal value:
Adult: 22-29mmol/L
Children: 18-27mmol/L

Above normal:
Found in respiratory acidosis.



Tips: Actively cooperate with the doctor during the examination. Normal value

Normal value:

Adult 22 ~ 29mmol / L.

Children 18 ~ 27mmol / L.

Clinical significance

Reduced: seen in metabolic acidosis (such as ketoacidosis in diabetic ketoacidosis, hunger ketotoxicity, renal insufficiency, severe diarrhea, intestinal fistula, extensive burns, etc.); respiratory alkalosis (eg by the brain) Inflammation, meningitis, cerebral hemorrhage, snoring, asthma, septic shock, epidemic hemorrhagic fever, etc.).

Elevation: seen in respiratory acidosis (eg caused by chronic bronchitis, obstructive emphysema, pulmonary heart disease, persistent bronchial asthma, bronchiectasis, extensive pulmonary fibrosis, lung consolidation, morphine poisoning, etc.); Metabolic alkalosis (such as caused by acute gastritis, pyloric obstruction, pregnancy vomiting, adrenal hyperfunction, hypokalemia, excessive consumption of basic drugs, excessive use of dexamethasone).

Low results may be diseases: acute respiratory failure in children, renal insufficiency, high respiratory failure results may be disease: pyloric obstruction precautions

Mild acidosis, CO2CP is 16 ~ 21mmol / L; moderate acidosis, CO2CP is 12 ~ 15mmol / L; severe acidosis, CO2CP is 7 ~ 11mmol / L; extreme acidosis, CO2CP is below 6mmol / L.

Inspection process

The venous blood of the patient is taken by using a clean test tube on an empty stomach, and the blood sample is centrifuged to separate into a plasma component and a blood cell component, and the upper layer is taken overnight, and under the condition of air isolation, the alveolar gas is balanced with a normal person, and then the carbon dioxide is detected by titration. Specific content.

Not suitable for the crowd

There are no special taboos.

Adverse reactions and risks

No related complications or hazards.