Total bilirubin is composed of unbound bilirubin and bound bilirubin, which is a bilirubin that does not bind to glucuronic acid. Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results.

Basic Information

Specialist classification: Digestive examination classification: biochemical examination

Applicable gender: whether men and women apply fasting: fasting

Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. Normal value

Less than 11.1 micromoles / liter (<0.65 mg / dl).

Clinical significance

Abnormal results:

1, increased in severe burns, sepsis, malaria, blood group incompatibility, spleen hyperfunction, pernicious anemia, globin-forming anemia, lead poisoning, neonatal physiological jaundice, drug-induced jaundice, constitutional jaundice, lactating jaundice, etc. .

2, total bilirubin and unconjugated bilirubin increased, hemolytic jaundice; total bilirubin and combined and unbound bilirubin increased, for hepatic jaundice; combined with bilirubin and total bilirubin Ratio, >35% is obstructive or hepatocellular jaundice; ratio <20% is hemolytic jaundice.

Need to check the crowd:

Severe burns, symptoms of jaundice.

Precautions

Note before inspection:

1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results.

2. After 8 pm on the day before the medical examination, you should fast.

3, the day before the inspection must not drink, drinking will lead to elevated transaminase, affecting the results of the examination.

Requirements for inspection:

1. Inform the doctor about the drug history, and some drugs affect the test results.

2, can not be checked after strenuous exercise, affecting the results.

Not suitable for people:

Patients who have taken drugs that affect liver metabolism within 3 days are not suitable for this test.

Inspection process

Principle: Bound bilirubin in serum can react with diazo reagent to form azo bilirubin, while conjugated bilirubin can form azo bilirubin with the help of a promoting or surfactant. These two bilirubins The sum of the total serum bilirubin.

Reagent: azo reagent (Ou Li area diazonium reagent).

Not suitable for the crowd

Taboo people:

Patients who have taken drugs that affect liver metabolism within 3 days are not suitable for this test.

Adverse reactions and risks

There are generally no special complications or hazards.