Calculating the ratio of direct bilirubin to total bilirubin helps to identify the type of jaundice. Total bilirubin, direct bilirubin, and indirect bilirubin are elevated, and are hepatocellular jaundice, such as acute severe hepatitis, chronic active hepatitis, cirrhosis, toxic hepatitis, and liver cancer. Total bilirubin and direct bilirubin are elevated, which are obstructive jaundice, such as biliary calculi, biliary obstruction, liver cancer, and pancreatic head cancer. Increased total bilirubin and indirect bilirubin, hemolytic jaundice, such as hemolytic anemia, blood group incompatibility, falciparum malaria, neonatal jaundice.

Basic Information

Specialist classification: Digestive examination classification: liver function test

Applicable gender: whether men and women apply fasting: fasting

Tips: Please cooperate with the doctor when checking. Normal value

Around 0.20.

Clinical significance

1, <0.20, found in hemolytic jaundice, congenital jaundice.

2, 0.20 ~ 0.60, found in hepatic jaundice and mixed jaundice.

3, >0.60, common in obstructive jaundice.

Low results may be diseases: high gallstone results may be diseases: hemolytic jaundice, cholestasis jaundice precautions

1, total bilirubin, direct bilirubin, indirect bilirubin are elevated, is a hepatocellular jaundice, such as acute severe hepatitis, chronic active hepatitis, cirrhosis, toxic hepatitis, liver cancer and so on.

2, total bilirubin and direct bilirubin increased, is obstructive jaundice, such as biliary calculi, biliary obstruction, liver cancer, pancreatic head cancer.

3, total bilirubin and indirect bilirubin increased, is hemolytic jaundice, such as hemolytic anemia, blood group incompatibility, falciparum malaria, neonatal jaundice.

Inspection process

2 ml of fasting venous blood was taken and placed in a dry tube for examination to avoid hemolysis of the specimen.

Detection method: After fully mixing, the wavelength is 600nm, the control tube is zeroed, and the absorbance of each tube is read; or the zero is adjusted with distilled water, the absorbance of the measuring tube and the control tube is read, and the difference between the absorbance of the measuring tube and the absorbance of the control tube is used (AU- AC), the corresponding bilirubin concentration was found on the standard curve.

Not suitable for the crowd

Generally no taboos.

Adverse reactions and risks

1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection.

2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.