Total bilirubin includes direct bilirubin and indirect bilirubin. Bilirubin is a metabolite of bile salts that is present in plasma and is associated with plasma color. When liver cell damage, bile duct obstruction, increased red blood cell destruction, or shortened lifespan, bilirubin metabolism often occurs abnormally, and jaundice appears clinically. The bilirubin metabolism test is mainly used to understand the presence or absence of jaundice, and to identify its type.

Basic Information

Specialist classification: Digestive examination classification: liver function test

Applicable gender: whether men and women apply fasting: fasting

Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. Normal value

3.4 to 17.1 μmol/L.

Clinical significance

Increased in toxic or viral hepatitis, hemolytic jaundice, pernicious anemia, paroxysmal hemoglobinuria. Polycythemia, neonatal jaundice, internal bleeding, hemolytic jaundice after transfusion, acute yellow liver atrophy. Congenital bilirubin metabolism abnormalities (Crigler-Najjar syndrome, Gilbert syndrome, Dubin-Johnson syndrome), fructose intolerance, etc., as well as intake of salicylic acid, erythromycin, rifampicin, progesterone, An Nai near drugs.

In particular, jaundice, which is generally less than 34 μmol/L, is not easily seen, and is called recessive jaundice; 34-170 pmol/L is mild jaundice; 170-340 μmol/L is moderate jaundice; >340 μmol/L It is highly jaundic. Complete obstructive jaundice 340 ~ 510μmol / L; incomplete obstruction 170 ~ 265μmol / L; hepatic jaundice 17 ~ 200μmol / L; hemolytic jaundice <85μmol / L.

High results may be diseases: pediatric familial non-hemolytic jaundice syndrome, congenital non-hemolytic jaundice precautions

First, the precautions before blood draw

1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results.

2. After 8 pm on the day before the physical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky.

3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection.

Second, should pay attention after blood draw

1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma.

2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended.

3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.

4. If there is localized congestion, use a warm towel after 24 hours to promote absorption.

Inspection process

Immediately after venous blood collection, the test is sent. Detection method: 4 ml of fresh blood was taken in a physiological saline test tube, and washed repeatedly with physiological saline for several times, and then repeatedly shaken by adding distilled water to completely dissolve the red blood cells (microscopic staining under the microscope), and the supernatant was aspirated after centrifugation.

Not suitable for the crowd

Generally no taboos.

Adverse reactions and risks

1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection.

2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.