Ovarian function test
Ovarian function tests include basal body temperature measurement of infertility, cervical mucus examination, and periodic vaginal smears. It is used to understand ovarian function, with or without ovulation, ovulation date and ovarian corpus luteum function.Basic Information
Specialist classification: gynecological examination classification: ultrasound
Applicable gender: whether women are fasting: not fastingAnalysis results:
No special disease tips.
Prompt for other diseases, it is recommended to check further.
1. Cervical mucus crystallization examination Under normal conditions, on the 8th to 10th day of the menstrual cycle, the mucus smear shows crystallization, and the estrogen level in the ovulation period peaks, and the smear shows typical fibrillar crystal. After ovulation, the crystallization gradually decreased, and the crystallization did not occur until 22 days. The amount of crystallization and the integrity of the fiddle shape suggest the level of estrogen in the body. In the normal menstrual cycle, the appearance and disappearance of mucus dentate crystals have certain regularity. Generally, atypical crystals appear on the tenth day of menstruation. As the level of estrogen in the body increases, it changes to a lower typical crystal. Typical dentate crystals can be seen during ovulation, and then turned into ovulation. More typical crystals, even atypical crystals, turn into ellipsoids on the 22nd day of the menstrual cycle.
2, ovulation mucus can be pulled to 7~10cm or more, and the mucus becomes thick after ovulation, that is, there is no drawing phenomenon.
3, women with normal ovulation, elevated body temperature should last 12-16 days.
There are many items for ovarian function tests. Only a few of them are listed here. You can view the examinations of ovarian function tests in detail.Clinical significance
1, cervical mucus crystallization examination clinically according to the degree of cervical mucus crystallization and the integrity of the fern to predict ovulation, diagnosis of pregnancy, estimation of early pregnancy prognosis, identification of amenorrhea type, diagnosis of dysfunctional uterine bleeding.
2, cervical mucus drawing test Where the cervical mucus is thin and transparent, long ductility, indicating the high impact of estrogen, lack of progesterone effect, suggesting no ovulation or pregnancy. When the mucus is as much as egg white, it is close to the ovulation period. If the viscosity of the mucus does not change much, it indicates that the level of estrogen is low and the ovarian function is incomplete.
3. The increase in body temperature lasts for less than 11 days, indicating that the development of the corpus luteum is not perfect.
There are many items for ovarian function tests. Only a few of them are listed here. You can view the examinations of ovarian function tests in detail.
People who need to be examined: amenorrhea, dysfunctional uterine bleeding, undeveloped corpus luteum or no ovulation.Positive results may be diseases: dry blood stasis, ovarian infertility, hyperprolactinemia, galactorrhea-menopausal syndrome, irregular menstruation, ovarian inflammation, amenorrhea amenorrhea syndrome, hydrosalpinx, amenorrhea, amenorrhea syndrome, tubal ligation Postoperative complications
Taboo before inspection:
1. Keep a normal diet and schedule, don't stay up late.
2, cervical mucus examination from the 7th day of the menstrual cycle to after ovulation to check, in order to understand the morphological changes of cervical mucus crystallization, the inspection time is longer, pay attention to go to the hospital on time.
Requirements for inspection:
1. Determination of basal body temperature of infertility The daily measurement time is preferably fixed. Night shift workers should measure their body temperature after 6-8 hours of sleep, and at least three menstrual cycles should be measured.
2, cervical mucus examination need to expose the cervix, at this time do not have to be too nervous, so as not to bring too much difficulty to the doctor's work.Inspection process
1. Basal body temperature After waking up in the morning, use body temperature to measure body temperature, record and draw the basal body temperature curve to understand ovarian function, with or without ovulation, ovulation date and ovarian corpus luteum function. Generally measured continuously for more than three months. Under normal circumstances, the first half of the menstrual cycle (ie follicular phase), the basal body temperature is low, about 36.5 ° C, lower in the ovulation period, after the ovulation, under the influence of progesterone, the body temperature rises to about 36.5 ° C ~ 37 ° C, until menstruation When the tide is rising, the change of the body temperature curve is called "biphasic body temperature", indicating that there is ovulation, the normal luteal phase is not less than 12 days, and the body temperature rise is not less than 0.3 to 0.5 °C. For example, if the body temperature does not rise in the second half of the menstrual cycle, it is called “single-phase body temperature”, indicating no ovulation. If the body temperature rises for more than 3 weeks without falling and amenorrhea, it may be pregnancy.
2. Cervical mucus examination Cervical mucus is secreted by the endometrial secretory cells of the neck, and is affected by the estrogen and progesterone secreted by the ovaries. Therefore, the amount of cervical mucus, transparency, viscosity, crystallization and changes of epithelial cells can be used to judge ovarian function. At present, the clinical form of cervical mucus is commonly used in the diagnosis of infertility, early pregnancy, amenorrhea and functional uterine bleeding. Use a forceps or vascular clamp to extend into the cervical canal 0.5cm to take the mucus, place it on the slide, and after drying, examine under the microscope
(1) Typical crystallization (+++) smears are straight and slender, with typical branches and leaves of typical fern, indicating that the estrogen level is high or high, close to or in the ovulation period.
(2) More typical crystals (++) Fern leaves are broad, thick and short and curved, indicating a moderate effect of estrogen, seen on the 10th day of the menstrual cycle.
(3) Atypical crystals (+) have more forms, or branches after rain, and the branches are short and sparse. Some are slender and curved, like goldfish grass, indicating that estrogen has a mild effect, more common in the short period after menstruation is clean.
(4) No crystals (-) only epithelial cells and white blood cells, indicating low levels of estrogen.
(5) The ellipsoidal body is 2 to 3 times longer than the white blood cells, and is elliptical in shape and arranged in a plurality of rows. It shows that the effect of progesterone after ovulation is about 30 days on the menstrual cycle. An ellipsoid appears, possibly a pregnancy.
3. Endometrial examination Take the endometrium 1 to 3 days before the first menstrual period or 12 hours before the first menstrual period. For example, the endometrium in the secretory phase indicates ovulation, and the proliferative endometrium has no ovulation.
4. Vaginal exfoliated cell examination (vaginal smear)
The vaginal epithelium is directly affected by ovarian endocrine secretion, and has different manifestations depending on the amount of estrogen and progesterone. Therefore, vaginal smear can be used to understand ovarian function. The degree of keratinization of vaginal epithelial cells is directly proportional to the level of estrogen in the body. Under the influence of estrogen, the cells gradually reach full differentiation and maturation, and the nucleus is dense and shrinking, and the cytoplasm is eosinophilic. Therefore, the keratinocyte index and the nuclear densification index on the smear reflect the level of estrogen in the body.
Smear from the vaginal wall, fixation, Pap staining, microscopic examination of keratinocytes <20% "light effects of estrogen". 20% to 60% are “moderately affected”; >60% are “highly impacted”. The vaginal keratinocytes of normal women of childbearing age change periodically. After the menstruation, the follicles gradually develop, the estrogen gradually increases, and the keratinocytes gradually increase, accounting for about 50% to 40% of the ovulation period, accounting for 50%. The acidic cytoplasm is mainly stained with red dense nucleus, and the cells are large, flat, scattered, and the background is clean. After ovulation, the keratinocytes decrease under the action of progesterone, and about 10-20% of the cells are wrinkled and the background is blurred. The increase in the middle layer of cells and the appearance of round bottom cells indicate ovarian dysfunction. When the underlying cells are <20%, the "estrogen is mildly low", the proportion of 20-40 is "moderately low" > 40% is "highly low" > 40% is "highly low" endocrine examination by vaginal exfoliated cells To provide reference for the diagnosis and treatment of functional uterine bleeding, amenorrhea and threatened abortion.
There are many items for ovarian function tests. Only a few of them are listed here. You can view the examinations of ovarian function tests in detail.Not suitable for the crowd
Inappropriate people: no menstrual period, no visible crystals during pregnancy, so pregnant women and menopause do not have to do cervical mucus examination.Adverse reactions and risks