About 10% to 15% of patients with myasthenia gravis (MG) have thymoma, and these patients have a higher risk of crisis. Because thymoma can be in a long-term stable state and lacks characteristic performance, it is difficult to diagnose. Some thymomas can be found on chest X-ray films. Even CT examinations sometimes have certain difficulties in identifying thymoma and thymic hyperplasia. The serum of MG patients contains a variety of autoantibodies against specific skeletal muscle components. CAEab is a common autoreactive antibody in the serum of MC patients with thymoma. It is called thymoma-related antibody and has a suggestion for MG patients with thymoma. Significant specificity.

Basic Information

Specialist classification: growth and development check classification: immunological examination

Applicable gender: whether men and women apply fasting: not fasting

Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. Normal value

CAEab titer <1:4.

Clinical significance

Disease management system

The CAEab titer was specifically increased in 1MG with thymoma, suggesting that CAEab is significantly specific for MG with thymoma.

2 Detection of CAEab titer is a sensitive and reliable indicator of immune diagnosis for early diagnosis of thymoma.

3 detection of CAEab may become an objective indicator of clinical efficacy observation.

Precautions

Experimental differential diagnosis: Different from lymphoid epithelial thymoma, the antibody titer of almost all lymphoid epithelial thymoma increased.

Inspection process

Same as indirect coagulation method.

Not suitable for the crowd

There are no taboos.

Adverse reactions and risks

There are no related complications and hazards.