It refers to antibodies against various nuclear components and is a widely existing autoantibody. Antinuclear antibody (ANA), also known as anti-nucleic acid antigen antibody, is a group of various components of eukaryotic cells, such as deoxyribonucleoprotein (DNP), DNA, extractable nuclear antigen (ENA) and RNA. The general term for autoantibodies of antigens can react with the nucleus of all animals, mainly in serum, but also in pleural fluid, joint synovial fluid and urine.

Basic Information

Specialist classification: growth and development check classification: immunological examination

Applicable gender: whether men and women apply fasting: fasting

Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. Normal value

Indirect immunofluorescence is less than 1:10 (negative).

Clinical significance

Increased in systemic lupus erythematosus, mixed connective tissue disease, scleroderma, rheumatoid arthritis, Sjogren's syndrome, drug-induced lupus (such as antiarrhythmic drug procainamide, antihypertensive drug hydralazine, treatment of epilepsy Pain medicine, lupus caused by anti-thyroid drugs such as thiouracil, etc.).


First, the precautions before blood draw:

1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results.

2. After 8 pm on the day before the physical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky.

3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection.

Second, after blood draw should pay attention to:

1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma.

2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended.

3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.

4. If there is localized congestion, use a warm towel after 24 hours to promote absorption.

Inspection process

Autoantibody detection.

Not suitable for the crowd

There are no taboos.

Adverse reactions and risks

There are no related complications and hazards.