Since cardiac muscle antigens release myocardial antigens and stimulate autoantibodies produced by the body, binding of these antibodies to the heart can lead to new immune damage. Positive in myocardial infarction syndrome, rheumatic heart disease and other diseases; short-term positive after heart surgery.

Basic Information

Specialist classification: cardiovascular examination classification: blood examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:

Normal value:
no

Above normal:

negative:
normal.

Positive:
Abnormal heart.

Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. Normal value

Indirect immunofluorescence is less than 1:10 (negative).

Clinical significance

Positive in myocardial infarction syndrome, rheumatic heart disease and other diseases; short-term positive after heart surgery.

Positive results may be diseases: neonatal myocarditis, rheumatic fever in children, pericarditis after myocardial infarction, dilated cardiomyopathy

Taboo before the test: Do not eat too greasy, high-protein food the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results.

Attention to check: After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.

Inspection process

Inspection method: indirect immunofluorescence:

Fluorescein is labeled on the corresponding antibody and reacts directly with the corresponding antigen.

In the first step, an unknown unlabeled antibody (sample to be tested) is added to a known antigen sample, incubated at 37 ° C for 30 min in a wet box, the antigen antibody is sufficiently bound, and then washed to remove unbound antibody.

In the second step, a fluorescently labeled anti-globulin antibody or an anti-IgG, IgM antibody is added. If an antigen-antibody reaction occurs in the first step, the labeled anti-globulin antibody will further bind to the antigen-bound antibody, thereby identifying an unknown antibody.

Not suitable for the crowd

Not suitable for the crowd: generally no special population.

Adverse reactions and risks

There are no related complications.