The patient's anti-insulin receptor antibody is present in patients with insulin-dependent syndrome, and insulin dependence is associated with anti-IRA in the patient's serum.

Basic Information

Specialist classification: Digestive examination classification: endocrine examination

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:

Normal value:
no

Above normal:

negative:
normal.

Positive:
diabetes.

Tips: Before the inspection taboo: should not eat foods with high sugar content, will directly affect the test results. Normal value

ELISA and RIA were negative.

Clinical significance

Positive insulin-dependent diabetes mellitus (type 1).

Positive results may be diseases: considerations for diabetes

Not suitable for the crowd: generally no special population.

Taboo before inspection: It is not advisable to eat foods with high sugar content, which will directly affect the test results.

Requirements for examination: When the serum to be tested contains anti-insulin antibodies at the same time, the results of the anti-insulin receptor antibody (IRA) are interfered with and need to be corrected by other methods.

Inspection process

ELISA method: the procedure is coated with purified human, pig or bovine crystalline insulin. The serum to be tested is diluted 1:10, and the optimal concentration of HRP-labeled anti-human IgC antibody or labeled anti-human IgA F (ab) is added. '): The substrate was developed with color, and the positive result was tested for the highest dilution of serum AIAb.

Not suitable for the crowd

There are no special taboos.

Adverse reactions and risks

There are no related complications and hazards.