Rubella is common in school-age children and adolescents, and more than 80% of the population is positive for this virus. Pregnant women are infected with rubella virus 20 weeks before pregnancy, and the incidence of fetal teratogenesis is higher. Adults and children infected with rubella can cause a rash. This test is a reference indicator for judging whether or not the rubella virus is infected, [reference value] is negative or lgGAb<1:512. The laboratory test for rubella virus is to detect IgG and IgM antibodies against rubella virus in vivo by taking venous blood.

Basic Information

Specialist classification: Infectious disease inspection and classification: pathogenic microorganism inspection

Applicable gender: whether men and women apply fasting: fasting

Analysis results:

Below normal:

Normal value:
no

Above normal:

negative:
Normally negative.

Positive:
Positive indicates a rubella virus infection.

Tips: The blood test should be fasted in the morning. Normal value

negative.

Clinical significance

Abnormal results:

Rubella-IgM positivity usually occurs within 2 weeks after infection, and peaks after rubella appear for one or two months; rubella-IgG positive usually occurs two or three weeks after infection. It reaches its peak within half a year and lasts for several years.

Need to check the crowd:

A patient with a rubella rash on the skin, pregnant women.

Positive results may be diseases: congenital rubella considerations

Preparation before inspection:

The blood test should be fasted in the morning.

Note when checking:

IgM antibodies should be detected within the 5th to 15th days of onset, with the highest positive rate. IgG antibody increased after 2 weeks of onset, so 1 blood test can be taken after 4 days and 15 days after onset, and satisfactory results can be obtained.

Not suitable for people:

Those who do not have an indication for examination should not do this check.

Inspection process

Enzyme-linked immunosorbent assay, referred to as ELISA. At its center is the combination of antibodies and enzyme complexes, which are then detected by color development. Step: ELISA is used to detect blood. First, the blood should be agglutinated for at least half an hour, then serum is taken to dilute the enzyme complex with a diluent, and serum and a negative, positive control, and quality control are added. After an hour of incubation, then wash the plate, add the substrate, half an hour to avoid the light reaction and add the stop solution to complete the reaction part, then the reading. The result is judged to be negative or positive by the value.

Not suitable for the crowd

Those who do not have an indication for examination should not do this check.

Adverse reactions and risks

Generally no complications and harm.