Matrix keratitis

Introduction

Introduction to stromal keratitis

Matrix keratitis is an inflammation located in the layer and is a non-ulcer deep keratitis. For different causes, carry out treatments such as driving plum, anti-tuberculosis and anti-rheumatic. Topical corticosteroids can be used for eye or subconjunctival injection. In addition, it is dilated, hot, and so on. For residual corneal scars, visual acuity is less than 0.1, optical keratoplasty may be considered. The treatment of the disease is mainly for different causes, for the treatment of plum, anti-tuberculosis, anti-rheumatic and other treatments. Topical corticosteroids can be used for eye or subconjunctival injection. In addition, it is dilated, hot, and so on. For residual corneal scars, visual acuity is less than 0.1, optical keratoplasty may be considered.

basic knowledge

Sickness ratio: 2%

Susceptible people: mostly young people aged 5 to 20

Mode of transmission: mother-to-child transmission

Complications: glaucoma, iridocyclitis, iritis, choroiditis

Pathogen

Cause of stromal keratitis

Cause:

Most of them are congenital syphilis, followed by tuberculosis, rheumatism and other infections. Pathogenic microorganisms can directly invade the cornea through epithelial or limbal vessels; but more are antigen-antibody reactions.

Prevention

Matrix keratitis prevention

In daily life, people should pay attention to labor protection. In the event of eye trauma, they must go to the hospital immediately, and should be treated by professionals. At the same time, avoid using unclean eye drops. Because Pseudomonas aeruginosa can contaminate and survive in various eye drops, such as Di Ao Ning, dicaine, cortisone, and even sulfonamide, penicillin, fluorescein, so in the corneal damage, use eye drops after several days of storage, especially fluorescein liquid is dangerous.

Complication

Matrix keratitis complications Complications glaucoma iridocyclitis iritis choroiditis

In the central area of the cornea, different degrees of scars are left, which affects vision; if the scar is dense or becomes flattened, it can seriously affect vision, and the corneal neovascularization becomes tapered and atrophy. After many years, it leaves a very fine gray silk in the deep cornea. Shaped shadow blood vessels, become a special sign of the disease forever, and some cases can cause secondary glaucoma due to concurrent rainbow ciliary inflammation.

The course of the disease is slow, and it can be repeated repeatedly in adulthood. At the end of the day, most of the cornea is involved. After the process, thicker, scars of different shades are left, and vision can be seriously affected.

Often accompanied by iritis, iridocyclitis and choroiditis, usually after 1 to 2 months, inflammation and neovascularization begin to resolve, leaving some corneal opacity, and vision loss.

Symptom

Matrix keratitis symptoms common symptoms ciliary congestion keratitis on the cornea point dark gray turbid saddle nose ear horn corneal opacity

1, syphilis : caused by congenital syphilis, the age of onset is mostly 5 to 20 years old, the two eyes at the same time or successively, accompanied by deafness, lower margin of the upper incisor, saddle nose and other characteristics, the latter two and the cornea Change composition; serum Kanghua reaction positive, acquired syphilis is rare, ocular lesions at the beginning, that is, there are obvious irritation symptoms, from the corneal periphery began to infiltrate, gradually extended to the central region, and finally meet in the corneal central region, the cornea The matrix is infiltrated, edema, grayish-white haze, loss of original luster, ciliary congestion or mixed hyperemia. With the development of corneal lesions, the neonatal deep blood vessels are seen as brush-like invading the corneal stroma from around the limbus. Gradually extended to the center of the cornea, the cornea becomes dark red frosted glassy turbidity, generally infiltrates to all corneas after two weeks, the inflammation reaches a peak in about 1 month; at the same time, it is covered with new blood vessels, the disease is always accompanied by iris eyelashes Stomatitis, recovery period, reduction of ciliary congestion, inflammation gradually subsides, absorption of corneal opacity, also from the peripheral part; corneal luster recovery after inflammation subsides Often, eventually, there are different degrees of scarring in the central area of the cornea, affecting vision; if the scar is dense or becomes flattened, it can seriously affect vision, and the corneal neovascularization becomes tapered and atrophy. After many years, it leaves a pole in the deep cornea. Fine grayish white silky shadow blood vessels have become a special symbol of the disease forever. In some cases, secondary glaucoma can be caused by concurrent rainbow ciliary body inflammation.

2, tuberculosis: more monocular onset, in the corneal stroma, the inferior layer infiltrates, initially close to the limbus, and then gradually develop into the center of the cornea, invasive turbidity is mostly nodular or clumpy, the number is uncertain, more limited In a certain area, unlike the full spread of syphilis, new blood vessels appear at the same time as inflammatory infiltration, and its distribution is also regional, less increased, and spheroidal coils around the nodular turbidity, the course of the disease is slow, Can be repeated for many years, and finally the majority of the cornea is involved, leaving a thicker, thicker scars, vision can be seriously affected.

Examine

Examination of stromal keratitis

In addition to the characteristic eye diagnosis, it can be confirmed from other signs of congenital syphilis such as saddle nose, Hutchinson's teeth and serum Kanghua reaction.

Diagnosis

Diagnosis and differentiation of stromal keratitis

diagnosis

Diagnosis can be based on medical history, clinical symptoms, and laboratory tests.

Differential diagnosis

Identification with vesicular keratitis, bacterial keratitis and various viral keratitis.