Scar cancer

Introduction

Introduction to scar cancer

Scar tissue is an inevitable outcome of the human wound repair process. Scar cancer is malignant on the basis of the formation of scar ulcer. It is several years old and is decades old, also known as malignant ulcer.

basic knowledge

Sickness ratio: 0.0001%

Susceptible people: no specific people

Mode of infection: non-infectious

Complications: Mildew

Pathogen

Causes of scar cancer

Causes:

Scar tissue malignant transformation is common in the following cases: 1. Unstable scar tissue after burn according to domestic and international records, the interval between burn and cancer, for more than 60 years, generally an average of 32 years. 2. Chronic ulcers of the lower limbs. 3. Scar tissue of chronic osteomyelitis sinus. 4. There is a high incidence of cancer on the basis of radiation ulcers.

Pathogenesis:

Scar cancer is mostly squamous cell carcinoma, a few are basal cell carcinoma, scar cancer is mostly squamous cell carcinoma after burn, and radioactive cancer is mostly basal cell carcinoma. The degree of differentiation of scar cancer is high, mainly showing local infiltration, but lymph node and blood transfer can also occur. .

Histopathology can be seen, on the edge of long-term unhealed ulcers, gradually bulging, keratinized proliferation or papillary hyperplasia, in squamous cell carcinoma, most of the more differentiated cancer cells, some of which are keratinized cancer beads; The cancer cells are surrounded by the base and the surrounding tight and dense scar tissue, and other parts are chronic inflammation or granulation tissue. The pathological morphology of scar cancer can be divided into three types:

1. Crater-like appearance: the ulcer base is uneven, the edge is crater-like, and the quality is hard, mostly squamous cell carcinoma.

2. Cauliflower pattern: the ulcer is papillary hyperplasia, the surface is uneven, the margin is everted, like cauliflower-like, mostly squamous cell carcinoma.

3. Insect-like appearance: the ulcer has an uneven base, the edges are not uniform, and the appearance seems to be bitten by insects, mostly the performance of basal cell carcinoma.

Prevention

Scar cancer prevention

The incidence of scar cancer is low, but patients can not be negligent, should pay attention to prevention, early detection, early treatment.

Chronic stimuli such as long-lasting wounds and unstable scars are important in the development of scar carcinogenesis. Therefore, patients should try to reduce the mechanical, chemical and thermal stimulation of patients. It is best to wear pure cotton products in underwear, try to avoid repeated Impermanence of pulling, rubbing, ulceration, and infection.

The incubation period of scar cancer is longer, and the malignant transformation is almost without repeated ulceration of the wound. The chronic ulcer stage of long-term unhealed, if the scar area is allergic and itchy, repeated ulceration and long-term unhealed, and ulcer secretions, stench, easy to touch Bleeding, appearance such as volcanic or cauliflower, with obvious necrosis, infection, etc. should be timely pathological examination, but need to be distinguished from ulcer infection.

To prevent scar cancer, in addition to early treatment of keloids, it should also protect the scar from long-term stimulation and repeated damage, and prevent chronic ulcers. Remember: repeated scratching is easy to induce cancer. Surgery, laser, freezing, skin transplantation, etc. Keloids not only increase the recurrence of keloids, but are also more susceptible to cancer.

Complication

Scar cancer complications Complications

Chronic inflammation, ulcers are open wounds, highly susceptible to bacterial contamination, combined with poor local blood supply to scars, infection is difficult to heal, forming chronic inflammation.

Symptom

Scar cancer symptoms Common symptoms Ulcer secretions, stenchy papillary hyperplasia changes, appearance of pus ulcers, crater-like papules, hyperesthesia, scars, ulcers, scars, scars

Scar cancer is the result of long-term unhealing and malignant ulceration. From scarring to carcinogenesis, the length of time varies. The shortest is 5 years, the elderly can reach 60 years, the average is 32 years. The older the patient, the more likely it is to occur. Cancerous.

Scar cancer occurs in the lower third of the lower leg, the heel, the joints of the limbs and other wearable parts, the scalp and the trunk are also good sites.

At the beginning of the local itching and scarring area allergic, ulcers appear in the scar after the damage, or gradually enlarged by the small papules, on the edge of the long-term unhealed ulcer, gradually bulging, keratinized proliferation or papillary hyperplasia, The appearance of the ulcer is crater-like, cauliflower-like and worm-like, and it is easy to bleed, and the surface can be covered with pus moss, and the secretion is stench.

The disease develops slowly, because the cancer cells are surrounded by the tough and dense scar tissue around the basement, so it is generally not easy to spread and metastasize. For example, once it expands into normal tissue, it spreads rapidly and spreads.

Examine

Scar cancer examination

Histopathological examination: Take multiple pieces of ulcers suspected of cancerous early, and cut the specimen several times in order to confirm the diagnosis as early as possible.

Pathological examination showed that squamous cell carcinoma is mostly squamous cell carcinoma, and a few are basal cell carcinoma. In squamous cell carcinoma, most of them are cancer cells with more complete differentiation, and some are keratinized cancer beads. The cancer cells are tough and dense by the base and the periphery. Surrounded by scar tissue, while other parts are chronic inflammation or granulation tissue.

Diagnosis

Diagnosis and diagnosis of scar cancer

Diagnostic criteria

1. History: Older patients with lower 1/3 of the calf, heel, scalp and other parts of the long-term unhealed scar ulcers, should be highly vigilant.

2. Typical clinical features: ulcers that occur on scars, the appearance of which is crater-like, cauliflower-like or worm-like; ulcer bleeding; ulcer secretions stench.

3. Pathological diagnosis: Scar cancer needs to be differentiated from benign skin ulcers and skin malignant tumors.

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