Phagocytosis

Introduction

Introduction to cutaneous epidermosis

Dermatophilosis is an infectious disease caused by Congolese faecium. It is mainly transmitted in animals and is caused by infections of livestock and wild animals. It has been found in Africa, Asia, Oceania, Europe and South America. It has been found that human infections are rare. In 1960, Dean et al found four patients in New York, USA, who developed the disease after contact with sick deer. The disease has a good prognosis and can heal without treatment. No cases of systemic infection have been found so far.

basic knowledge

The proportion of illness: 0.08%

Susceptible people: no special people

Mode of infection: non-infectious

complication:

Pathogen

Cause of cutaneous epidermosis

(1) Causes of the disease

Epidermidis actinomycetes, the typical strain is Congoles pneumoniae, its main feature is aerobic or facultative anaerobic, the internal mycelium is thick, 0.5 ~ 5m, by the hard gelatin capsule Wrapped, split apart, matured mycelium split into fragments and spheroids, in the appropriate conditions into a moving spore (walking spores), spore diameter 0.5 ~ 1m, apical 5 ~ 7 flagella, germination The hyphae are undulating and have a sulcus. The spores can germinate in the mycelium. Under artificial culture conditions, the mycelium divides vertically and transversely to produce a flat body, and lateral splitting produces a lateral branch.

(two) pathogenesis

The skin-infecting bacteria invade the human body and germinate into hyphae. The mycelium divides vertically and divides to produce a flat body, and the lateral splitting produces lateral branches. When suitable conditions are met, the spores can germinate in the mycelium and become viable spores. Spores), causing damage, when the damage is broken, it is a pale red crater-like appearance, accompanied by yellowish white pus exudation. During the recovery process, brown scars appear first, lasting for several days to one week. Form a scar with a fuchsia.

Prevention

Prevention of cutaneous epidermosis

Avoid contact with cattle, horses, deer and goats. If symptoms appear after contact, treat them as soon as possible. Early detection and early diagnosis are the key to the prevention and treatment of this disease.

Complication

Complications of cutaneous epidermosis Complication

Scars form after the wound heals.

Symptom

Symptoms of cutaneous epithelial disease Common symptoms The appearance of congestive ulcers is crater-like pus-like pustules

The cutaneous epidermosis often occurs in animals such as cows, horses, deer and goats. It may occur when people are exposed to diseased animals. They are usually exposed for 2 to 7 days. On one or both sides of the hand, most of the forearms are painless. White papules or pustules, 2 to 5 mm in diameter, with a congestive zone around them. When the damage is broken, it has a pale red crater-like appearance, accompanied by yellowish white pus exudation. During the recovery process, a brown knot first appears. Hey, lasts for a few days to a week, forming a scar with a fuchsia.

Examine

Examination of cutaneous epidermosis

Skin lesion exudate smear, Giemsa staining microscopy and isolation culture, the colony is white or gray, then orange to yellow, Gram stain positive, not acid resistant, cell wall type III, sugar type ( Containing Madura sugar), using bovine heart infusion blood agar in aerobic and 5% to 10% carbon dioxide gas, culture at 37 ° C grew well, showing aerial hyphae, culture growth at 27 ° C slower, Cultured with sand castle agar did not grow.

Diagnosis

Diagnosis and identification of cutaneous epidermosis

According to epidemiological history, history of contact with animals, typical clinical manifestations, lesion exudate smear, Giemsa staining microscopy and isolation and culture identification confirmed.

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