High transpeptidase



The function of the spinase: the formation of peptide bonds during protein biosynthesis has a necessary role. Transpeptidase recognizes specific polypeptides and catalyzes different transpeptidation reactions. It is widely distributed in the body, such as kidney, liver, pancreas and other organs. However, GGT in serum is mainly from the liver and has strong specificity. Therefore, when the hepatobiliary system is diseased, the GGT activity is elevated, and the enzyme activity is clinically determined to assist in the diagnosis of hepatobiliary diseases.



First, the physiologically induced transpeptidase is high:

For example, when obstructive jaundice occurs, the enzymes will be abnormal and will flow back into the blood, and the transpeptidase will be high; in addition, the transpeptidase caused by hepatobiliary disease is high.

Common diseases are viral hepatitis, cirrhosis, cholangitis, primary hepatitis, and extra-biliary tuberculosis.

Second, non-pathologically caused by high transpeptidase:

If you drink a lot of alcohol regularly, the transpeptidase will be temporarily elevated. This situation usually stops after normal drinking.

It can be seen that there are many reasons for the high transpeptidase. In particular, further comprehensive examination should be carried out. According to the results of the examination, the condition should be judged and effective measures should be taken to reduce the harm of the disease to the body.


an examination

Related inspection

Serum -glutamyl transpeptidase liver function test serum leucine aminotranspeptidase (LAP)

Examination of serum -glutamyl transpeptidase can be performed.


Differential diagnosis

Can be identified with increased transaminase.

When hepatocytes undergo inflammation, necrosis, poisoning, etc., causing damage to the liver cells, the transaminase is released into the blood, causing the serum transaminase to rise.

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